Sanaz Gabery, PhD

Photo: Tove Smeds

Employment

2022: Novo Nordisk, Denmark

2019 - 2022: Post doctoral fellow - Hjärnfonden (Brain Foundation) stipendee

2018: Research scientist, TNU, Medical Faculty, Lund University, Sweden

2016 - 2017: Novo Nordisk, Denmark.

2015: Assistant researcher, TNU, Medical Faculty, Lund University, Sweden

Education

2017 - 2022: Medical programme, Medical Faculty, Lund University, Sweden

2011 - 2015: PhD studies in Neuroscience, Medical Faculty, Lund University, Sweden.
Thesis: New perspectives on pathology in Huntington's disease - characterization of hypothalamic changes.
Supervisor: Associate Professor Åsa Petersén MD PhD, TNU.
 
2010: Master of Medical Science in biomedicine, major in experimental medicine, Lund university, Lund.
Thesis: Investigation of neuropathological changes in the hypothalamus and forebrain in Huntington’s disease. 
Supervisor: Åsa Petersén MD PhD, Translational Neuroendocrine Research Unit (TNU).

2008: Bachelor in Medical Science, major: Biomedicine, Lund university, Lund.
Thesis: Role of different brain regions in Huntington’s disease - initial studies using adenoassociated viral vector expression of GFP and heterozygote HAP1 mice. 
Supervisor: Åsa Petersén MD PhD, Translational Neuroendocrine Research Unit (TNU).
 
2004: High school diploma , major: natural science, Malmö Borgarskola, Malmö.

Publications

Bergh S, Gabery S, Tonetto S, Kirik D, Petersén Å and Cheong RY.
Effects of mutant huntingtin in oxytocin neurons on non-motor features of Huntington's disease.
Neuropathology and Applied Neurobiology. 2023 Feb 12;e12891. doi: 10.1111/nan.12891. Online ahead of print.

Bergh S, Cheong R Y, Petersén Å and Gabery S.
Oxytocin in Huntington’s disease and the spectrum of amyotrophic lateral sclerosis-frontotemporal dementia.
Front. Mol. Neurosci., 14 September 2022; Sec. Molecular Signalling and Pathways. doi.org/10.3389/fnmol.2022.984317

Gabery S, Kwa JE, Cheong RY, Baldo B, Ferrari Bardile C, Tan B, McLean C, Georgiou-Karistianis N, Poudel GR, Halliday G, Pouladi MA and Petersén Å.
Early white matter pathology in the fornix of the limbic system in Huntington disease.
Acta Neuropathologica. 142(5): 791-806 (2021) doi: 10.1007/s00401-021-02362-8.

Gabery S,  Ahmed RA, Caga J,  Kiernan MC, Halliday GM and Petersén Å. 
Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis.
Neuropathology and Applied Neurobiology. 47(7): 979-989 (2021) doi.org/10.1111/nan.12709

Fjalldal S, Rylander L, van Westen D, Holmer H, Follin C, Gabery S, Petersen Å and Erfurth E M.
Brain white matter lesions are associated with reduced hypothalamic volume and cranial radiotherapy in childhood onset craniopharyngioma.
Clinical Endocrinology (Oxf) 94 (1): 48-57 (2021)

Sanaz Gabery, Casper G. Salinas, Sarah J. Paulsen, Jonas Ahnfelt-Rønne, Tomas Alanentalo, Arian F. Baquero, Stephen T. Buckley, Erzsébet Farkas, Csaba Fekete, Klaus S. Frederiksen, Hans Christian C. Helms, Jacob F. Jeppesen, Linu M. John, Charles Pyke, Jane Nøhr, Tess T. Lu, Joseph Polex-Wolf, Vincent Prevot, Kirsten Raun, Lotte Simonsen, Gao Sun, Anett Szilvásy-Szabó, Hanni Willenbrock, Anna Secher and Lotte Bjerre Knudsen.
Semaglutide lowers body weight in rodents via distributed neural pathways.
JCI Insight. 5(6): Doi: 10.1172/jci.insight.133429. (2020)

Cheong RY, Gabery S and Petersén Å.
The Role of Hypothalamic Pathology for Non-Motor Features of Huntington's Disease.
Journal of Huntington's disease 8 (4): 375-391 (2019)

Baldo B, Gabery S, Soylu-Kucharz R, Cheong RY, Henningsen JB, Englund E, McLean C, Kirik D, Halliday G and Petersén Å.
SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease.
Neuropathology and Applied Neurobiology 45 (4): 361-379 (2019)

Fjalldal S, Follin C, Gabery S, Sundgren PC, Björkman-Burtscher IM, Lätt J, Mannfolk P, Nordström CH, Rylander L, Ekman B, Cheong R, Pålsson A, Petersén Å and Erfurth EM.
Detailed assessment of hypothalamic damage in craniopharyngioma patients with obesity.
International Journal of Obesity (Lond). 2019 43: 533-544 (2019) 

Baldo B, Gabery S, Soylu-Kucharz R, Cheong RY, Henningsen JB, Englund E, McLean C, Kirik D, Halliday G and Petersén Å.
SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease.
Neuropathology and Applied Neurobiology. 2018 Jul 18. doi: 10.1111/nan.12514. [Epub ahead of print]

Fjalldal S, Follin C, Svärd D, Rylander L, Gabery S, Petersen Å, Van Westen D, Sundgren P, Bjorkman-Burtscher I, Lätt J, Ekman B, Johanson A and Erfurth EM.
Microstructural white matter alterations and hippocampal volumes are associated with cognitive deficits in craniopharyngioma.
European Journal of Endocrinology 178 (6): 577-587 (2018)

Follin C, Fjalldal S, Svärd D, van Westen D, Gabery S, Petersén Å, Lätt J, Rylander L and Erfurth EM.
Microstructure alterations in the Hypothalamus in cranially radiated Childhood Leukemia survivors but not in Craniopharyngioma patients unaffected by hypothalamic damage. 
Clinical Endocrinology. 87(4): 359-366 (2017)

Rochel B, Domínguez D J F, Stout J, Gabery S, Churchyard A, Chua P, Egan G, Petersén A, Georgiou-Karistianis N and Poudel G R.
Subjective sleep problems in Huntington's disease: A pilot investigation of the relationship to brain structure, neurocognitive, and neuropsychiatric function.
Journal of the Neurological Sciences 364: 148-153 (2016)

Follin C, Gabery S, Petersén Å, Sundgren PC, Björkman-Burtcher I, Lätt J, Mannfolk P and Erfurth EM.
Associations between Metabolic Risk Factors and the Hypothalamic Volume in Childhood Leukemia Survivors Treated with Cranial Radiotherapy.
PLoS One. Jan 29;11(1):e0147575 (2016)

Gabery S, Georgiou-Karistianis N, Lundh SH, Cheong RY, Churchyard A, Chua P, Stout JC, Egan GF, Kirik D and Petersén Å.
Volumetric Analysis of the Hypothalamus in Huntington Disease Using 3T MRI: The IMAGE-HD Study.
PLoS One 10(2) (2015)

Gabery S, Halliday G, Kirik D, Englund E, Petersén Å.
Selective loss of oxytocin and vasopressin in the hypothalamus in early Huntington disease: a case study.
Neuropathol Appl Neurobiol. 41(6): 843-848 (2015)

Gabery S, Sajjad MU, Hult S, Soylu R, Kirik D and Petersén Å.
Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
European Journal of Neuroscience 36(6):2789-800 (2012)

Petersen Å and Gabery S.
Hypothalamic and limbic system changes in Huntington's disease.
Journal of Huntington's disease 1: 13-24 (2012)

Piguet O, Petersén A, Yin Ka Lam B, Gabery S, Murphy K, Hodges JR and Halliday GM. 
Eating and hypothalamus changes in behavioral-variant frontotemporal dementia. 
Annals of Neurology 69: 312-319 (2011) 

Gabery S, Murphy K, Schultz K, Loy CT, McCusker E, Kirik D, Halliday G and Petersén Å.
Changes in key hypothalamic neuropeptide populations in Huntington disease revealed by neuropathological analyses. 
Acta Neuropathologica 120: 777-788 (2010)